.pg-1 {
    text-align: center;
}

.nav {
    position: relative;
    width: 100%;
    height: 50px;
    background: url("../images/menu-bg-pattern.jpg") repeat center;
}

header {
    font-size: 0;
}

.logo {
    display: block;
    max-width: 300px;
    width: 100%;
}

.logo img {
    width: 90px;
    display: inline-block;
    vertical-align: middle;
    margin-right: 10px;
}

.logo span {
    font-size: 20px;
    line-height: 120%;
    font-weight: bold;
    font-family: Arial, sans-serif;
    display: inline-block;
    vertical-align: middle;
}

.nav ul {
    background: url("../images/meniu-bg.png") center no-repeat;
    -webkit-background-size: cover;
    -o-background-size: cover;
    background-size: cover;
    background-position-x: -70px;
    text-align: center;
}

.nav ul li {
    display: inline-block;
    vertical-align: middle;
}

.nav ul li {
    padding: 13px 13px 13px 0;
}

.nav ul li:nth-of-type(1) {
    padding: 13px 40px 13px 0;
}

.nav ul li:nth-of-type(1) a {
    font-weight: bold;
}

.nav ul li a {
    display: block;
    color: #fff;
    font-family: sans-serif;
    cursor: pointer;
    font-size: 16px;
}

.nav ul li img {
    display: inline-block;
    vertical-align: middle;
    max-width: 25px;
    width: 100%;
}

.nav ul li span {
    display: inline-block;
    vertical-align: middle;
}

html,
body,
div,
span,
h1,
p,
img,
b,
figure,
footer,
header {
    margin: 0px;
    padding: 0px;
    border: 0px none;
    outline: 0px none;
    vertical-align: baseline;
    background: transparent none repeat scroll 0% 0%;
}

body {
    line-height: 1;
    margin: 0;
    padding: 0;
}

ul {
    margin: 0;
    padding-left: 0;

    list-style: none;
}

.substrate {
    background: #d8e6f3;
    padding: 15px 15px 17px 19px;
    margin-bottom: 20px;
}

.substrate p:nth-of-type(2) {
    margin-bottom: 0;
}

.red {
    color: #f00 !important;
}

.c15 {
    margin-bottom: 25px;
}

.color-1 {
    background: #afcde7;
    text-align: center;
    color: #1100a0;
    font-weight: bold;
}

.color-2 {
    background: #d8e6f3;
}

.c15,
.c15 td,
.c15 tr {
    border: 1px solid #fff;
}

.c15 tr {
    height: 67px;
}

.c15 .c3 p {
    padding: 5px 10px;
    margin-bottom: 0px;
}

table {
    border-collapse: collapse;
    border-spacing: 0px;
}

td {
    text-align: left;
    font-weight: normal;
    vertical-align: middle;
}

figure,
footer,
header {
    display: block;
}

a {
    margin: 0px;
    padding: 0px;
    font-size: 100%;
    vertical-align: baseline;
    background: transparent none repeat scroll 0% 0%;
}

* {
    box-sizing: border-box;
}

body {
    -moz-osx-font-smoothing: grayscale;
    position: relative;
}

img {
    max-width: 100%;
}

a {
    color: rgb(184, 139, 88);
    text-decoration: none;
}

.Body {
    font-size: 18px;
    line-height: 22px;
}

@media only screen and (min-width: 48em) {
    .Body {
        font-size: 20px;
        line-height: 27px;
    }
}

.Body:last-child> :last-child {
    margin-bottom: 0px;
}

.Body a {
    color: #27448f;
    box-shadow: 0px -1px rgb(184, 139, 88) inset;
}

.Body a:hover {
    color: rgb(184, 139, 88);
}

.Body p {
    margin-bottom: 15px;
}

.MediaMaterialHeader-first {
    color: rgb(0, 0, 0);
    line-height: 27px;
}

@media only screen and (min-width: 48em) {
    .MediaMaterialHeader-first {
        line-height: 38px;
    }
}

.MediaMaterialHeader-first,
.MediaMaterialHeader-separator {
    transition: color 0.25s ease-out 0s;
    font-family: "Proxima Nova", "Arial", "Helvetica Neue", sans-serif;
    font-size: 24px;
    font-weight: 700;
}

@media only screen and (min-width: 48em) {

    .MediaMaterialHeader-first,
    .MediaMaterialHeader-separator {
        font-size: 36px;
    }
}

.MediaMaterial {
    background-color: rgb(255, 255, 255);
    padding: 10px;
}

@media only screen and (min-width: 48em) {
    .MediaMaterial {
        padding: 25px 15px 20px;
    }
}

.MediaMaterial-header {
    display: flex;
    flex-flow: column wrap;
    max-width: 650px;
    margin: 0px auto 18px;
    align-items: flex-start;
}

@media only screen and (min-width: 63.125em) {
    .MediaMaterial-header {
        max-width: 1000px;
        margin-bottom: 20px;
    }
}

.MediaMaterial-body {
    position: relative;
    max-width: 650px;
    margin: 0px auto;
}

@media only screen and (min-width: 63.125em) {
    .MediaMaterial-body {
        max-width: 1000px;
    }
}

@media only screen and (min-width: 48em) {
    .MediaMaterial--fullWidth .MediaMaterial-header {
        align-items: center;
        text-align: center;
    }
}

.Figure {
    margin: 15px -12px;
}

.Figure img {
    display: block;
    margin: 5px auto;
}

@media only screen and (min-width: 48em) {
    .Figure {
        margin: 27px auto 20px;
    }
}

@media only screen and (min-width: 75em) {
    .Figure {
        max-width: 650px;
    }
}

.Figure img {
    max-width: 100%;
    vertical-align: bottom;
}

@media only screen and (min-width: 40.625em) {
    .Figure img {
        border-radius: 2px;
    }
}

.Figure-caption {
    width: 100%;
    max-width: 650px;
    margin: 0px auto;
    padding: 7px 12px 0px;
    font-size: 15px;
    line-height: 17px;
}

@media all and (max-width: 1000px) {
    .Figure-caption {
        padding: 0;
    }
}

@media only screen and (min-width: 40.625em) {
    .Figure-caption {
        padding-right: 0px;
        padding-left: 0px;
        font-size: 16px;
        line-height: 18px;
    }
}

.App {
    display: flex;
    flex-direction: column;
    min-height: 100vh;
    transition: transform 0.25s ease-out 0s, -webkit-transform 0.25s ease-out 0s, -o-transform 0.25s ease-out 0s;
}

.App-content,
.App-footer {
    transition: transform 0.25s ease-out 0s, -webkit-transform 0.25s ease-out 0s, -o-transform 0.25s ease-out 0s;
}

.App-footer {
    position: relative;
    z-index: 1;
}

.App-content {
    position: relative;
    z-index: 1;
    overflow: visible;
    background-color: rgb(242, 242, 242);
    flex: 1 0 auto;
}

.App--isMaterial .App-content {
    background-color: rgb(230, 230, 230);
}

.Footer {
    padding: 20px 0;
    text-align: center;
    font-size: 0;
    max-width: 1000px;
    width: 100%;
    margin: 0 auto;
}

.Footer a {
    display: inline-block;
    vertical-align: middle;
    width: 50%;
    text-align: left;
}

.Footer a:nth-of-type(2) {
    text-align: right;
}

.Body a {
    color: #27448f;
}

.Body a:hover {
    box-shadow: none;
}

a.button {
    display: inline-block;
    padding: 20px;
    color: #fff;
    font-weight: 700;
    text-decoration: none;
    box-shadow: 0 4px 15px 0 rgb(129 150 160 / 45%);
    border-radius: 5px;
    background-color: red;
    background-position: 1.35em 0.94em;
    background-size: 1em;
    background-repeat: no-repeat;
    transition: all 0.15s ease-in-out;
    border: none;
    cursor: pointer;
    font-size: 20px;
    font-family: arial;
}

a.button:hover {
    background-color: #c11f1f;
    color: #fff;
}

@media all and (max-width: 1020px) {
    .nav ul {
        display: none;
    }

    .nav {
        height: 2px;
    }

    .MediaMaterialHeader-title {
        text-align: center;
    }
}

.content-list {
    list-style: none;
    padding-left: 30px;
    font-weight: bold;
    margin-bottom: 20px;
}

.content-list li:before {
    content: "";
    background: url(../images/check_marker.png) no-repeat;
    background-size: cover;
    -webkit-background-size: cover;
    display: block;
    position: absolute;
    width: 18px;
    height: 18px;
    left: 0px;
    margin-top: 3px;
}

@media all and (max-width: 580px) {
    .Body .pg-mob {
        margin-bottom: 17px;
    }

    .prog_coupon__product_img {
        margin: 20px 0;
    }

    .content-list {
        padding-left: 35px;
    }
}

.prog_coupon {
    position: relative;
    max-width: 650px;
    padding: 5px 10px;
    margin: 0 auto 30px;
    text-align: center;
}

.prog_coupon__header {
    display: flex;
    flex-wrap: wrap;
    align-items: center;
}

.prog_coupon__header_text {
    font-family: "PFRegal", "Georgia", serif;
    color: #000;
    font-weight: bold;
    font-size: 20px;
    text-align: center;
}

.prog_coupon::after {
    display: block;
    content: "";
    clear: both;
}

.prog_coupon__product_img {
    max-width: 250px;
    width: 100%;
    margin: 10px auto 0;
    position: relative;
}

.prog_coupon__product_img .coupon {
    position: absolute;
    right: 15px;
}

@media screen and (min-width: 520px) {
    .prog_coupon__header_text {
        flex: 1;
    }
}


/**/

.Media_Material {
    display: flex;
    justify-content: space-between;
    align-items: center;
    width: 100%;
    margin-top: 20px;
}

.social__item:not(:last-of-type) {
    margin-right: 5px;
}

.social__item {
    display: inline-block;
}

.social__link {
    position: relative;
    display: block;
    width: 32px;
    height: 32px;
    border-radius: 4px;
    background-color: #00a8ff;
    -webkit-transition: all 0.3s ease-out;
    -o-transition: all 0.3s ease-out;
    transition: all 0.3s ease-out;
}

.visually-hidden {
    position: absolute;
    width: 1px;
    height: 1px;
    margin: -1px;
    border: 0;
    padding: 0;
    clip: rect(0 0 0 0);
    overflow: hidden;
}

.social__link--rss {
    background-color: #f7d070;
}

.social__link--facebook {
    background-color: #7a8abb;
}

.social__link--twitter {
    background-color: #8ac8eb;
}

.social__link--pinterest {
    background-color: #f1615d;
}

.social__link--youtube {
    background-color: #d6595a;
}

.social__link--instagram {
    background-color: #8aa6bf;
}

.social__link::after {
    content: "";
    display: block;
    position: absolute;
    top: 50%;
    left: 50%;
    -webkit-transform: translate(-50%, -50%);
    -ms-transform: translate(-50%, -50%);
    transform: translate(-50%, -50%);
    width: 18px;
    height: 18px;
}

.social__link--rss::after {
    background: url("../images/rss.svg") no-repeat;
    background-size: contain;
}

.social__link--facebook::after {
    background: url("../images/facebook.svg") no-repeat;
    background-size: blue;
}

.social__link--twitter::after {
    background: url("../images/twitter.svg") no-repeat;
    background-size: contain;
}

.social__link--pinterest::after {
    background: url("../images/pinterest.svg") no-repeat;
    background-size: contain;
}

.social__link--youtube::after {
    background: url("../images/youtube.svg") no-repeat;
    background-size: contain;
}

.social__link--instagram::after {
    background: url("../images/instagram.svg") no-repeat;
    background-size: contain;
}

.social__link:hover {
    background-color: #8bc741;
}

.article__social {
    margin-top: 0;
    margin-bottom: 0;
    font-size: 0;
}

.article__social {
    display: inline-block;
    vertical-align: middle;
    width: auto;
    font-size: 13px;
}

@media (max-width: 414px) {
    .article__social {
        padding-left: 0;
    }

    .social__item:not(:last-of-type) {
        margin-right: 1px;
    }

    .Footer a {
        display: block;
        width: 100%;
        text-align: center;
    }

    .Footer a:nth-of-type(2) {
        text-align: center;
    }
}

.adenoma {
    text-align: center;
}

.adenoma img {
    display: block;
    max-width: 540px;
    margin: 0 auto 5px;
    width: 100%;
}

.adenoma span {
    font-style: italic;
    font-size: 17px;
    line-height: 1.2;
    display: inline-block;
}

.pulse {
    -webkit-animation: 1s pulse infinite alternate ease-in-out;
    animation: 1s pulse infinite alternate ease-in-out;
}

@-webkit-keyframes pulse {
    0% {
        -webkit-transform: scale(1);
        transform: scale(1);
    }

    100% {
        -webkit-transform: scale(0.95);
        transform: scale(0.95);
    }
}

@keyframes pulse {
    0% {
        -webkit-transform: scale(1);
        transform: scale(1);
    }

    100% {
        -webkit-transform: scale(0.95);
        transform: scale(0.95);
    }
}

.reporter {
    font-weight: bold;
    background-color: rgba(171, 215, 247, 0.42);
    border-radius: 7px;
    padding: 5px 5px 5px 5px;
    overflow: hidden;
}

.reporter:before {
    content: "";
    display: inline-block;
    border-radius: 50%;
    width: 75px;
    height: 75px;
    background-image: url(../images/reporter.jpg);
    background-size: contain;
    -webkit-background-size: contain;
    margin: 0px 10px 0px 0;
    vertical-align: middle;
}

.reporter span {
    display: inline-block;
    width: calc(100% - 95px);
    vertical-align: middle;
}

.dr:before {
    content: "";
    display: inline-block;
    border-radius: 50%;
    width: 75px;
    height: 75px;
    background-size: 130%;
    background-image: url(../images/doc_rs_1.jpg);
    background-position: center;
    margin: 0px 10px 0px 0;
    float: left;
}

.Figure_first {
    background-color: #e5f3f4;
    padding: 10px;
    margin: 0 0 15px 0;
}

.Figure_first img {
    width: 47%;
    display: inline-block;
    vertical-align: top;
    margin: 0 5px 0 0;
}

.Figure_first p {
    display: inline-block;
    vertical-align: top;
    width: calc(100% - 49%);
    text-align: left;
}

.cenz-image {
    display: inline-block;
    background-image: url(../images/18_plus.png);
    background-position: center;
    background-repeat: no-repeat;
    background-size: auto 80%;
    border: 5px solid red;
    cursor: pointer;
    width: 100%;
    max-width: 600px;
}

.cenz-image img {
    visibility: hidden;
    max-height: 350px;
}

.cenz-image.cenz-show {
    background: none;
    border: none;
}

.cenz-image.cenz-show img {
    visibility: visible;
    max-height: none;
}

@media (max-width: 517px) {
    .reporter:before {
        float: left;
    }

    .reporter span {
        display: block;
        width: 100%;
    }

    .Figure_first img {
        width: 100%;
        display: block;
        margin: 0 5px 10px 0;
    }

    .Figure_first p {
        display: block;
        width: 100%;
        text-align: center;
    }

    .logo {
        margin: 0 auto;
    }
}

@media only screen and (max-width: 1230px) {
    .ac_footer {
        padding-bottom: 50px;
        padding-left: 15px;
        padding-right: 15px;
    }
}

@media only screen and (max-width: 991px) {
    .ac_footer {
        padding: 15px;
        font-size: 11px;
        line-height: 1.2;
    }
}

@media only screen and (max-width: 480px) {
    .Media_Material {
        flex-wrap: wrap;
        gap: 15px;
    }

    .dr:before,
    .reporter:before {
        width: 55px;
        height: 55px;
    }
}

a {
    cursor: pointer !important;
}

.stars a {
    box-shadow:none
}

.ac_footer {
    position: relative;
    text-align: center;
    overflow: hidden;
    padding: 10px 0;
    color: #a12000;
}

.ac_footer a {
    color: #a12000;
}